Advertisement for Research Association Positions

A Research Associate position (possibly two) is available to work on structural studies of proline catabolic enzymes in the laboratory of Professor Jack Tanner of the Chemistry Department at the University of Missouri-Columbia.  The successful candidate must have a Ph.D. and a strong background in protein crystallography.  Applicants should submit curriculum vitae, summary of research experience and contact information for three references via e-mail to tannerjj@missouri.edu.  Include the words "research associate" in the subject of the message. Consideration of applications will begin immediately and continue until the position(s) are filled.  The University of Missouri is an Equal Opportunity/Affirmative Action/ADA employer. 

Here is a list of some of our publications on this project:

58. J.J. Tanner
Review article: Structural biology of proline catabolism
Amino Acids (2008) Mar 28 [Epub ahead of print]
PDF
PubMed Abstract

57.  Y. Zhou, J.D. Larson, C.A. Bottoms, E.C. Arturo, M.T. Henzl, J.L. Jenkins, J.C. Nix, D.F. Becker, and J.J. Tanner
Structural Basis of Transcriptional Regulation of the Proline Utilization Regulon by Multifunctional PutA
J. Mol. Biol. (2008) 381(1):174-88.
PDF
PubMed Abstract

56.  T.A. White, W.H. Johnson, Jr., C.P. Whitman and J.J. Tanner
Structural basis for the inactivation of Thermus thermophilus proline dehydrogenase by N-propargylglycine
Biochemistry (2008) 47(20):5573-80.
PDF
PubMed Abstract

49. T.A. White, N. Krishnan, D.F. Becker and J.J. Tanner
Structure and Kinetics of Monofunctional Proline Dehydrogenase from Thermus thermophilus.
J. Biol. Chem. (2007) 282(19):14316-14327.
PDF
PubMed Abstract

48. W. Zhang, M. Zhang, W. Zhu, Y. Zhou, S. Wanduragala, D. Rewinkel, J.J. Tanner and D.F. Becker
Redox-induced changes in flavin structure and roles of the flavin N(5) and the ribityl 2'-OH group in regulating PutA-membrane binding
Biochemistry (2007) 46(2):483-491.
PDF
PubMed Abstract

47. J.D. Larson, J.L. Jenkins, J.P. Schuermann, Y. Zhou, D.F. Becker and John J. Tanner
Crystal structures of the DNA-binding domain of Escherichia coli proline utilization A flavoprotein and analysis of the role of Lys9 in DNA recognition 
Protein Sci. (2006), 15:1–12.
PDF
PubMed Abstract

34. M. Zhang, T.A. White, J.P. Schuermann, B.A. Baban, D.F. Becker, and J. J. Tanner
Structures of the Escherichia coli PutA proline dehydrogenase domain in complex with competitive inhibitors.
Biochemistry (2004) 43(39) 12539-48.
PDF
PubMed abstract

33. B. Baban, M.P. Vinod, J.J. Tanner, and D.F. Becker
Probing a hydrogen bond pair and the FAD redox properties in the proline dehydrogenase domain of Escherichia coli PutA
Biochem. Biophys. Acta (2004) 1701, 49-59.
PDF
PubMed abstract

26.  Y.-H. Lee, S. Nadaraia, D. Gu, D. F. Becker, and  J. J. Tanner
Structure of the proline dehydrogenase domain of the multifunctional PutA flavoprotein
Nature Structural Biology (2003) 10, 109-114. 
PDF
PubMed abstract